⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10182573 | 1.00 | — | — | |
| SCHEMBL2021592 | 1.00 | — | — | |
| Hydrogen Sulfide SCHEMBL9272622 | 0.97 | TSHR (0.44) | — | |
| SCHEMBL17166001 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL21728769 | 0.77 | — | — | |
| SCHEMBL13697034 | 0.76 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL22045856 | 0.76 | KMT2A (0.47) | — | |
| SCHEMBL19711770 | 0.76 | KMT2A (0.47) | — | |
| SCHEMBL14589097 | 0.75 | CYP19A1 (0.39) | — | |
| SCHEMBL21300707 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210000966-A1 | HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2021-01-07 | — | — | US | disclosed |
| US-20190125888-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2019-05-02 | — | — | US | disclosed |
| US-20170151339-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2017-06-01 | — | — | US | disclosed |
| EP-3130608-A1 | (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE | Daiichi Sankyo Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |
| WO-2014075137-A1 | PEPTIDES INCORPORATING AMINO-SUBSTITUTED LACTAMS FOR TREATMENT OF RETINOPATHY | BIODIEM LIMITED (AU) | 2014-05-22 | — | — | WO | disclosed |
| EP-1529042-B1 | ARYLAMIDES | INTERMED DISCOVERY GMBH (DE) | 2013-02-20 | — | — | EP | disclosed |
| US-20120136042-A1 | CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC (US) | 2012-05-31 | — | — | US | disclosed |
| US-20090149528-A1 | Cinnamic acid amides | BAYER HEALTHCARE AG (DE) | 2009-06-11 | — | — | US | disclosed |
| US-20090149528-A1 | Cinnamic acid amides | BAYER HEALTHCARE AG (DE) | 2009-06-11 | — | — | US | disclosed |
| US-20090149528-A1 | Cinnamic acid amides | BAYER HEALTHCARE AG (DE) | 2009-06-11 | — | — | US | disclosed |
| US-7348357-B2 | bactericide; derivatives of pseudopeptide Andrimid in which beta-phenylalanine amide is replaced by heteroaromatic or substituted aromatic amide; N-{(1S)-3-[((1S)-1-{[(3R,4S)-1,4-Dimethyl-2,5-dioxo-3-pyrrolidinyl]carbonyl}-2-methylpropyl)amino]-3-oxo-1-phenylpropyl}-2-pyridinecarboxamide; antibiotics | BAYER HEALTHCARE AG (DE) | 2008-03-25 | — | — | US | disclosed |
| EP-1501795-B1 | CINNAMIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1501795-B1 | CINNAMIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| US-20060178369-A1 | Cinnamic acid amides | INTERMED DISCOVERY GMBH (DE) | 2006-08-10 | — | — | US | disclosed |
| US-20060173040-A1 | Arylamides | BAYER HEALTHCARE AG (DE) | 2006-08-03 | — | — | US | disclosed |
| EP-1529042-A1 | ARYLAMIDES | Bayer HealthCare AG (DE) | 2005-05-11 | — | — | EP | disclosed |
| EP-1501795-A1 | CINNAMIC ACID AMIDES | Bayer Aktiengesellschaft (DE) | 2005-02-02 | — | — | EP | disclosed |
| WO-2004113290-A1 | SUBSTITUTED ALKYLAMIDES | BAYER HEALTHCARE AG (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004020432-A1 | ARYLAMIDES | BAYER HEALTHCARE AG (DE) | 2004-03-11 | — | — | WO | disclosed |
| WO-2003091212-A1 | CINNAMIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2003-11-06 | — | — | WO | disclosed |