Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 9/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353835 | 1.00 | RAB9A (0.45) | RAB9AGLSRXFP1MAPTLMNA | |
| SCHEMBL22479672 | 0.92 | RAB9A (0.45) | RAB9AGLSRXFP1P2RX7 | |
| SCHEMBL29353907 | 0.88 | RAB9A (0.45) | RAB9AGLSGRM5 | |
| SCHEMBL21394590 | 0.88 | RAB9A (0.45) | RAB9AGLSGRM5 | |
| SCHEMBL29356718 | 0.88 | RAB9A (0.45) | RAB9AGLSMAPTFSCN1 | |
| SCHEMBL21394591 | 0.88 | RAB9A (0.45) | RAB9AGLSMAPTFSCN1 | |
| SCHEMBL29357147 | 0.88 | RAB9A (0.47) | RAB9AGLSMAPTLMNAP2RX7 | |
| SCHEMBL21394495 | 0.88 | RAB9A (0.47) | RAB9AGLSMAPTLMNAP2RX7 | |
| SCHEMBL21394513 | 0.88 | RAB9A (0.47) | RAB9AGLSMAPTLMNA | |
| SCHEMBL29358510 | 0.88 | RAB9A (0.47) | RAB9AGLSMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |