Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356922 | 1.00 | RAB9A (0.42) | RAB9APARP1CSF1RELANEMAPK1 | |
| SCHEMBL29358581 | 0.88 | RAB9A (0.44) | RAB9APARP1 | |
| SCHEMBL21394559 | 0.88 | RAB9A (0.44) | RAB9APARP1 | |
| SCHEMBL22479693 | 0.87 | RAB9A (0.45) | RAB9APARP1CSF1RDEGS1 | |
| SCHEMBL21394773 | 0.86 | RAB9A (0.44) | RAB9APARP1MAPK1 | |
| SCHEMBL29354631 | 0.86 | RAB9A (0.44) | RAB9APARP1MAPK1 | |
| SCHEMBL29353770 | 0.86 | RAB9A (0.44) | RAB9APARP1CSF1RMAPK1TP53 | |
| SCHEMBL21395053 | 0.86 | RAB9A (0.44) | RAB9APARP1CSF1RMAPK1TP53 | |
| SCHEMBL21394808 | 0.85 | RAB9A (0.47) | RAB9APARP1DEGS1 | |
| SCHEMBL29359190 | 0.85 | RAB9A (0.47) | RAB9APARP1DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |