Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395214 | 0.89 | DEGS1 (0.53) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL21394721 | 0.85 | SIRT2 (0.44) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL21395068 | 0.85 | NPC1 (0.48) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL21394937 | 0.84 | SIRT2 (0.42) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL29442822 | 0.84 | SIRT2 (0.50) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL21384381 | 0.84 | SIRT2 (0.50) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL21394696 | 0.82 | RAB9A (0.52) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL21395131 | 0.80 | CYP3A4 (0.43) | CYP3A4SIRT2 | |
| SCHEMBL29182427 | 0.80 | NPC1 (0.42) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL21394763 | 0.79 | NPC1 (0.51) | NPC1RAB9AALDH1A1PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |