Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.41 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395130 | 0.89 | NPC1 (0.40) | CACNA1HRAB9AGRM5NPC1SMN1; SMN2 | |
| SCHEMBL21394742 | 0.87 | MAPT (0.44) | CACNA1HFSCN1GRM4GPR6RAB9A | |
| SCHEMBL21394693 | 0.85 | SIRT2 (0.37) | GRM5RIPK1SIRT2 | |
| SCHEMBL21395129 | 0.84 | GRM5 (0.40) | RAB9AGRM5NPC1SMN1; SMN2KDM4E | |
| SCHEMBL22479679 | 0.83 | NPC1 (0.42) | RAB9AGRM5NPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29353664 | 0.80 | GRM4 (0.43) | CACNA1HGRM4GPR6RAB9AGRM5 | |
| SCHEMBL21395200 | 0.80 | GRM4 (0.43) | CACNA1HGRM4GPR6RAB9AGRM5 | |
| SCHEMBL21395028 | 0.79 | MAPT (0.45) | CACNA1HRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL21394959 | 0.79 | TMPRSS4 (0.49) | GRM4SIRT2 | |
| SCHEMBL21395011 | 0.78 | GRM4 (0.43) | CACNA1HGRM4SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |