Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 6/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394742 | 0.92 | MAPT (0.44) | MAPTALDH1A1TSHRL3MBTL1RAB9A | |
| SCHEMBL21394634 | 0.92 | TSHR (0.43) | MAPTALDH1A1TSHRL3MBTL1RAB9A | |
| SCHEMBL21395128 | 0.88 | L3MBTL1 (0.43) | MAPTALDH1A1TSHRL3MBTL1RAB9A | |
| SCHEMBL29355468 | 0.86 | L3MBTL1 (0.46) | MAPTALDH1A1TSHRL3MBTL1RAB9A | |
| SCHEMBL21394578 | 0.86 | L3MBTL1 (0.46) | MAPTALDH1A1TSHRL3MBTL1RAB9A | |
| SCHEMBL21394628 | 0.85 | ALDH1A1 (0.41) | MAPTALDH1A1TSHRL3MBTL1EP300 | |
| SCHEMBL29357585 | 0.85 | ALDH1A1 (0.41) | MAPTALDH1A1TSHRL3MBTL1EP300 | |
| SCHEMBL21394707 | 0.85 | MAPT (0.42) | MAPTALDH1A1TSHRL3MBTL1EP300 | |
| SCHEMBL21394572 | 0.85 | TSHR (0.44) | MAPTALDH1A1TSHRL3MBTL1RAB9A | |
| SCHEMBL29357109 | 0.85 | TSHR (0.44) | MAPTALDH1A1TSHRL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |