Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394656 | 0.89 | MEN1 (0.45) | PPARGNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL21394746 | 0.87 | PPARG (0.39) | PPARGNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL21395038 | 0.86 | ABCB1 (0.41) | NPC1RAB9AABL1SMN1; SMN2BRD4 | |
| SCHEMBL21394717 | 0.86 | CACNA1H (0.39) | PPARGNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL21395010 | 0.86 | TMPRSS4 (0.44) | PPARGNPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL21394999 | 0.86 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394718 | 0.84 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21395019 | 0.81 | PARP1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21395025 | 0.80 | NPC1 (0.45) | PPARGNPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL21394724 | 0.78 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |