Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394999 | 0.89 | NPC1 (0.46) | KDM4ENPC1ALDH1A1PKMTSHR | |
| SCHEMBL21395034 | 0.87 | ABCB1 (0.37) | ABCB1KDM4EABCC1NPC1ALDH1A1 | |
| SCHEMBL21394712 | 0.86 | PPARG (0.41) | KDM4ENPC1ALDH1A1PKMTSHR | |
| SCHEMBL21394393 | 0.83 | NPC1 (0.43) | ABCB1KDM4EABCC1NPC1ALDH1A1 | |
| SCHEMBL21394724 | 0.81 | NPC1 (0.48) | KDM4ENPC1ALDH1A1PKMTSHR | |
| SCHEMBL21395009 | 0.80 | PARP1 (0.53) | ABCB1KDM4EABCC1NPC1ALDH1A1 | |
| SCHEMBL21394395 | 0.79 | KDM4E (0.49) | ABCB1KDM4EABCC1NPC1ALDH1A1 | |
| SCHEMBL21394847 | 0.79 | NPC1 (0.50) | KDM4ENPC1ALDH1A1PKMTSHR | |
| SCHEMBL21395183 | 0.79 | NPC1 (0.47) | KDM4ENPC1ALDH1A1PKMTSHR | |
| SCHEMBL29355531 | 0.79 | NPC1 (0.50) | KDM4ENPC1ALDH1A1PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |