Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356245 | 0.86 | RAB9A (0.46) | RAB9AMAPTSMN1; SMN2LMNAHDAC3 | |
| SCHEMBL21394444 | 0.86 | RAB9A (0.46) | RAB9AMAPTSMN1; SMN2LMNAHDAC3 | |
| SCHEMBL21394773 | 0.84 | RAB9A (0.44) | RAB9AMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL29354631 | 0.84 | RAB9A (0.44) | RAB9AMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL21394748 | 0.84 | RAB9A (0.42) | RAB9AMAPTLMNANPC1FSCN1 | |
| SCHEMBL29356684 | 0.84 | RAB9A (0.42) | RAB9AMAPTLMNANPC1FSCN1 | |
| SCHEMBL22479454 | 0.82 | RAB9A (0.41) | RAB9AMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL29356951 | 0.82 | RAB9A (0.55) | RAB9AMAPTFSCN1KMT2AKDM4E | |
| SCHEMBL21394401 | 0.82 | RAB9A (0.55) | RAB9AMAPTFSCN1KMT2AKDM4E | |
| SCHEMBL21394665 | 0.81 | RAB9A (0.50) | RAB9AMAPTLMNANPC1FSCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |