Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.50 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31215048 | 0.85 | MAPK1 (0.57) | MAPTMAPK1KDM4EL3MBTL1GABRA5 | |
| SCHEMBL23537708 | 0.85 | MAPK1 (0.57) | MAPTMAPK1KDM4EL3MBTL1GABRA5 | |
| SCHEMBL65277 | 0.84 | NNMT (0.68) | MAPTMAPK1KDM4EL3MBTL1GABRA5 | |
| SCHEMBL23537880 | 0.83 | MAPK1 (0.56) | MAPTMAPK1KDM4EL3MBTL1GABRA5 | |
| SCHEMBL796493 | 0.82 | MAPT (1.00) | MAPTL3MBTL1GABRA5NNMTALDH1A1 | |
| SCHEMBL1092552 | 0.82 | MAPT (0.74) | MAPTMAPK1L3MBTL1NNMTALDH1A1 | |
| SCHEMBL19590814 | 0.82 | MAPK1 (0.54) | MAPTMAPK1KDM4EL3MBTL1GABRA5 | |
| SCHEMBL23538185 | 0.82 | MAPK1 (0.54) | MAPTMAPK1KDM4EL3MBTL1GABRA5 | |
| SCHEMBL4843142 | 0.82 | MAPK1 (0.54) | MAPTMAPK1KDM4EL3MBTL1GABRA5 | |
| SCHEMBL1091622 | 0.81 | MAPT (0.68) | MAPTGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |