Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.47 |
| ▸ | VNN1 | O95497 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384146 | 0.85 | RAB9A (0.63) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL21394822 | 0.78 | NPC1 (0.51) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL29442815 | 0.78 | NPC1 (0.51) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL21384064 | 0.75 | RAB9A (0.62) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL21384037 | 0.74 | NPC1 (0.60) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL21384221 | 0.74 | NPC1 (0.60) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL1753019 | 0.74 | NPC1 (0.86) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL2308761 | 0.73 | NPC1 (0.68) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL24460958 | 0.73 | CLK4 (0.53) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL16290847 | 0.73 | NPC1 (0.58) | RAB9ANPC1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |