Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394644 | 0.90 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTF10MEN1 | |
| SCHEMBL21395174 | 0.89 | HCAR2 (0.46) | ALDH1A1LMNAMAPTF10MEN1 | |
| SCHEMBL21394754 | 0.88 | NPC1 (0.46) | ALDH1A1RAB9ANPC1SNCAKDM4E | |
| SCHEMBL29358598 | 0.88 | NPC1 (0.46) | ALDH1A1RAB9ANPC1SNCAKDM4E | |
| SCHEMBL30862004 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTF10MEN1 | |
| SCHEMBL21384215 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTF10MEN1 | |
| SCHEMBL29357039 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTF10MEN1 | |
| SCHEMBL21394749 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTF10MEN1 | |
| SCHEMBL21394703 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTF10MEN1 | |
| SCHEMBL21394767 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTF10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |