Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 7/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395185 | 0.96 | TMPRSS4 (0.49) | TMPRSS4SIRT2MEN1KMT2ABACE1 | |
| SCHEMBL21395016 | 0.89 | CHEK1 (0.40) | TMPRSS4SIRT2 | |
| SCHEMBL21395002 | 0.89 | TMPRSS4 (0.41) | TMPRSS4SIRT2 | |
| SCHEMBL29442822 | 0.88 | SIRT2 (0.50) | TMPRSS4SIRT2MEN1KMT2A | |
| SCHEMBL21384381 | 0.88 | SIRT2 (0.50) | TMPRSS4SIRT2MEN1KMT2A | |
| SCHEMBL21394745 | 0.85 | TMPRSS4 (0.39) | TMPRSS4SIRT2 | |
| SCHEMBL29357585 | 0.85 | ALDH1A1 (0.41) | SIRT2MEN1KMT2A | |
| SCHEMBL21395196 | 0.84 | TMPRSS4 (0.52) | TMPRSS4SIRT2MEN1KMT2ABACE1 | |
| SCHEMBL21394959 | 0.84 | TMPRSS4 (0.49) | TMPRSS4SIRT2MEN1KMT2ABACE1 | |
| SCHEMBL29357102 | 0.84 | TMPRSS4 (0.52) | TMPRSS4SIRT2MEN1KMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |