Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667739 | 0.83 | PTGS1 (0.54) | SMN1; SMN2SLC6A2LMNATP53MAPT | |
| SCHEMBL11208153 | 0.83 | PTGS1 (0.54) | SMN1; SMN2SLC6A2LMNATP53MAPT | |
| SCHEMBL8012723 | 0.82 | TAAR1 (0.65) | TAAR1CHRM2CHRM1CHRM3CMA1 | |
| SCHEMBL30128872 | 0.82 | TAAR1 (0.65) | TAAR1CHRM2CHRM1CHRM3CMA1 | |
| SCHEMBL11561760 | 0.81 | TAAR1 (0.55) | TAAR1CHRM2CHRM1CHRM3CMA1 | |
| SCHEMBL27642642 | 0.81 | TAAR1 (0.68) | TAAR1CHRM2CHRM1CHRM3CMA1 | |
| SCHEMBL1951994 | 0.80 | LDHA (0.53) | CMA1IDO1ALDH1A1SMN1; SMN2SLC6A4 | |
| SCHEMBL10519767 | 0.79 | TAAR1 (0.57) | TAAR1CHRM2CHRM1CHRM3CMA1 | |
| SCHEMBL3827847 | 0.79 | KMT2A (0.53) | TAAR1MEN1KMT2A | |
| SCHEMBL10501393 | 0.78 | TAAR1 (0.64) | TAAR1CHRM2CHRM1CHRM3CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |
| CN-1898221-A | Modulators of atp-binding cassette transporters | VERTEX PHARMA (US) | 2007-01-17 | — | — | CN | disclosed |