Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 11/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 8/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394578 | 0.93 | L3MBTL1 (0.46) | L3MBTL1CACNA1HTSHRNPC1RAB9A | |
| SCHEMBL29355468 | 0.93 | L3MBTL1 (0.46) | L3MBTL1CACNA1HTSHRNPC1RAB9A | |
| SCHEMBL21395191 | 0.88 | CSNK1D (0.43) | L3MBTL1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29353720 | 0.88 | SNCA (0.48) | L3MBTL1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21384504 | 0.88 | SNCA (0.48) | L3MBTL1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21384407 | 0.86 | L3MBTL1 (0.43) | L3MBTL1CACNA1HCACNA1GCACNA1ITSHR | |
| SCHEMBL29356947 | 0.86 | L3MBTL1 (0.43) | L3MBTL1CACNA1HCACNA1GCACNA1ITSHR | |
| SCHEMBL29356645 | 0.85 | L3MBTL1 (0.47) | L3MBTL1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21394832 | 0.85 | L3MBTL1 (0.47) | L3MBTL1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21394677 | 0.84 | TSHR (0.43) | L3MBTL1CACNA1HCACNA1GCACNA1ITSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |