Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395194 | 0.91 | L3MBTL1 (0.45) | L3MBTL1GRM5TSHRTDP1MEN1 | |
| SCHEMBL21395033 | 0.88 | L3MBTL1 (0.45) | L3MBTL1GRM5TSHRTDP1MEN1 | |
| SCHEMBL21394572 | 0.87 | TSHR (0.44) | L3MBTL1GRM5TSHRTDP1MEN1 | |
| SCHEMBL29357109 | 0.87 | TSHR (0.44) | L3MBTL1GRM5TSHRTDP1MEN1 | |
| SCHEMBL21394399 | 0.87 | KMT2A (0.47) | L3MBTL1TSHRGCKTDP1MEN1 | |
| SCHEMBL21394741 | 0.87 | L3MBTL1 (0.55) | L3MBTL1TSHRTDP1MEN1KMT2A | |
| SCHEMBL21394735 | 0.87 | L3MBTL1 (0.43) | L3MBTL1GRM5TSHRTDP1MEN1 | |
| SCHEMBL21395157 | 0.85 | CYP3A4 (0.47) | L3MBTL1GRM5TSHRGCKCYP1A2 | |
| SCHEMBL22479581 | 0.84 | MEN1 (0.50) | L3MBTL1TSHRGCKTDP1MEN1 | |
| SCHEMBL21395158 | 0.82 | L3MBTL1 (0.42) | L3MBTL1GRM5TSHRTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |