Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394711 | 0.88 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL29358350 | 0.88 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL22479679 | 0.85 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394641 | 0.85 | TSHR (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL29356991 | 0.85 | TSHR (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL29357078 | 0.85 | KMT2A (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394475 | 0.85 | KMT2A (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394940 | 0.85 | SNCA (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394639 | 0.85 | FPR1 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL21394996 | 0.82 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |