Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | F10 | P00742 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395068 | 0.87 | NPC1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL21394767 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AF10 | |
| SCHEMBL29358525 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AF10 | |
| SCHEMBL21394718 | 0.85 | NPC1 (0.42) | ALDH1A1SMN1; SMN2F10NPC1RAB9A | |
| SCHEMBL21395193 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AF10 | |
| SCHEMBL29356935 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AF10 | |
| SCHEMBL21394466 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AF10 | |
| SCHEMBL21394393 | 0.81 | NPC1 (0.43) | ALDH1A1SMN1; SMN2NPC1RAB9APKM | |
| SCHEMBL21395015 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AF10 | |
| SCHEMBL21394749 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |