Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356949 | 0.87 | ABCC8 (0.46) | ABCC8KCNJ11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL21384455 | 0.87 | ABCC8 (0.46) | ABCC8KCNJ11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL21384424 | 0.86 | ABCC8 (0.47) | ABCC8KCNJ11SMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL29356186 | 0.86 | ABCC8 (0.47) | ABCC8KCNJ11SMN1; SMN2ALDH1A1MMP13 | |
| SCHEMBL21394446 | 0.85 | ABCC8 (0.39) | ABCC8KCNJ11SMN1; SMN2ALDH1A1ADRA1A | |
| SCHEMBL29355321 | 0.85 | ABCC8 (0.39) | ABCC8KCNJ11SMN1; SMN2ALDH1A1ADRA1A | |
| SCHEMBL29358116 | 0.83 | TSHR (0.47) | ABCC8KCNJ11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL21394582 | 0.83 | TSHR (0.47) | ABCC8KCNJ11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL21394511 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9AP2RY14 | |
| SCHEMBL29353756 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9AP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |