SCHEMBL21395986

SCHEMBL21395986

Cc1cc(-c2ccccc2)ccc1NC(C)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.49
SLC1A2 P43004 2/20 0.49
SLC1A1 P43005 2/20 0.49
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
ALOX12 P18054 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
HDAC1 Q13547 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
KDM4E B2RXH2 1/20 0.38
APOBEC3A P31941 1/20 0.38
GFER P55789 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
MCHR1 Q99705 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20120169 0.86 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1ALDH1A1GAA
SCHEMBL31091223 0.77 SLC1A3 (0.49) SLC1A3SLC1A2SLC1A1ALDH1A1GAA
SCHEMBL10050770 0.76 MEN1 (0.48) ALDH1A1GAAMAPTALOX12SMN1; SMN2
SCHEMBL18934066 0.76 HTR6 (0.49) SLC1A3SLC1A2SLC1A1ALDH1A1GAA
SCHEMBL26385190 0.75 NPC1 (0.48) ALDH1A1GAAMAPTKDM4E
SCHEMBL2230553 0.75 NPC1 (0.48) ALDH1A1GAAMAPTKDM4E
SCHEMBL19422614 0.74 SLC1A3 (0.47) SLC1A3SLC1A2SLC1A1ALDH1A1GAA
SCHEMBL6515938 0.74 KDM4E (0.45) ALDH1A1GAAMAPTKDM4E
SCHEMBL24685150 0.73 GAA (0.59) SLC1A3SLC1A2SLC1A1ALDH1A1GAA
SCHEMBL12303167 0.73 GAA (0.54) SLC1A3SLC1A2SLC1A1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019183358-A2 WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2019-09-26 WO disclosed