Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27980498 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL26681993 | 0.82 | SMN1; SMN2 (0.82) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL27179099 | 0.82 | NAMPT (0.65) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL5573222 | 0.81 | MAPT (0.76) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL19700727 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL1136833 | 0.80 | MAPT (0.64) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL3807661 | 0.80 | MAPT (0.64) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL13242366 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL22591163 | 0.79 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL20306312 | 0.79 | MAPT (0.62) | SMN1; SMN2MEN1KMT2ACYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180686-A1 | IDO-TDO DUAL INHIBITOR AND RELATED METHODS OF USE | CMG PHARMACEUTICAL CO., LTD. (KR) | 2019-09-26 | — | — | WO | disclosed |