Sugi Predict

Sugi Predict / Compounds / SCHEMBL1136833

SCHEMBL1136833

SCHEMBL1136833

CC(C)(C)OC(=O)N1CCN(c2ccc(CO)cc2)CC1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.64
▸ LMNA P02545 3/20 0.64
▸ ALDH1A1 P00352 1/20 0.64
▸ SMN1; SMN2 Q16637 4/20 0.62
▸ MEN1 O00255 3/20 0.62
▸ KMT2A Q03164 3/20 0.62
▸ CYP2C19 P33261 1/20 0.62
▸ HTT P42858 1/20 0.61
▸ NPSR1 Q6W5P4 1/20 0.61
▸ GPR119 Q8TDV5 10/20 0.56
▸ DDB1 Q16531 1/20 0.56
▸ CRBN Q96SW2 1/20 0.56
▸ NAMPT P43490 1/20 0.55
▸ TSHR P16473 1/20 0.52
▸ ESRRB O95718 1/20 0.52
▸ ESR1 P03372 1/20 0.52
▸ ESRRA P11474 1/20 0.52
▸ ESRRG P62508 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.50
▸ GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5573222 0.89 MAPT (0.76) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL23355487 0.89 MAPT (0.61) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL3807661 0.89 MAPT (0.64) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL3487758 0.88 GPR119 (0.75) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL1019005 0.87 MAPT (0.62) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL20306312 0.87 MAPT (0.62) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL3124993 0.87 MAPT (0.58) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL31544598 0.86 MAPT (0.61) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL8858016 0.86 MAPT (0.61) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL3709870 0.86 MAPT (0.61) MAPTLMNAALDH1A1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4717317-A2 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2026-04-01 — — EP disclosed
EP-3641762-B1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION C4 THERAPEUTICS INC (US) 2026-02-18 — — EP disclosed
US-20260015362-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2026-01-15 — — US disclosed
US-12441740-B2 N/O-linked degrons and degronimers for protein degradation C4 THERAPEUTICS, INC. (US) 2025-10-14 — — US disclosed
US-12324845-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2025-06-10 — — US disclosed
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-22 — — US disclosed
US-20250101037-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2025-03-27 — — US disclosed
US-12180225-B2 N/O-linked degrons and degronimers for protein degradation C4 THERAPEUTICS, INC. (US) 2024-12-31 — — US disclosed
CN-118440096-A Degradation stator and degradation determinant for N/O-ligation of protein degradation C4医药公司 2024-08-06 — — CN disclosed
US-11795174-B2 Anti-pain compound and preparation method thereof LUNAN PHARMACEUTICAL GROUP CORPORATION (CN) 2023-10-24 — — US disclosed
EP-0912175-A4 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO INC (US) 1999-09-08 — — EP disclosed
EP-0912175-A1 FIBRINOGEN RECEPTOR ANTAGONISTS Merck & Co., Inc. (US) 1999-05-06 — — EP disclosed
US-5854245-A Fibrinogen receptor antagonists MERCK & CO., INC. (US) 1998-12-29 — — US disclosed
WO-1998000134-A1 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1998-01-08 — — WO disclosed
US-5622950-A Pyrrolo-pyridine derivatives MERCK, SHARP & DOHME LTD. (GB) 1997-04-22 — — US disclosed
US-5576319-A Pyrrolo-pyridine derivatives MERCK, SHARP & DOHME LTD. (GB) 1996-11-19 — — US disclosed
CN-1118598-A Pyrrolopyridine Derivatives MERCK SHARP & DOHME (GB) 1996-03-13 — — CN disclosed
US-5432177-A Pyrrolo-pyridine derivatives MERCK SHARPE & DOHME LTD. (GB) 1995-07-11 — — US disclosed
EP-0623618-A2 Pyrrolo-pyridine derivatives MERCK SHARP & DOHME LTD. (GB) 1994-11-09 — — EP disclosed
WO-1994020497-A1 PYRROLO-PYRIDINE DERIVATIVES MERCK SHARP & DOHME LIMITED (GB) 1994-09-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12441740-B2 N/O-linked degrons and degronimers for protein degradation CRBN, CBL, STUB1 MAPT 3822/4885LMNA 1209/4885ALDH1A1 4548/4885
US-20250101037-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION CRBN, CBL, STUB1 MAPT 3822/4885LMNA 1209/4885ALDH1A1 4548/4885
US-12180225-B2 N/O-linked degrons and degronimers for protein degradation CRBN, CBL, STUB1 MAPT 3822/4885LMNA 1209/4885ALDH1A1 4548/4885
US-20260015362-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION CRBN, CBLC, CBL MAPT 4527/4885LMNA 921/4885ALDH1A1 4035/4885
US-11795174-B2 Anti-pain compound and preparation method thereof OPRK1, OPRM1, OPRL1 MAPT 482/4885LMNA 4622/4885ALDH1A1 1216/4885
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 MAPT 1201/4885LMNA 1041/4885ALDH1A1 798/4885
US-12324845-B2 Ligands for imaging cardiac innervation CHRNB4, RXFP4, RXFP3 MAPT 4188/4885LMNA 3406/4885ALDH1A1 3732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.