Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21396314 | 0.88 | NPC1 (0.53) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL16639790 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL21396303 | 0.85 | KDM4E (0.72) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL21396305 | 0.83 | NPC1 (0.53) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL21378565 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL21378563 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL21396318 | 0.80 | MAPK1 (0.51) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL18656446 | 0.80 | GAA (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL21396482 | 0.79 | NPC1 (0.48) | KDM4ELMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12296309 | 0.78 | CYP2C9 (0.61) | LMNASMN1; SMN2MAPTGAANAPEPLD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180686-A1 | IDO-TDO DUAL INHIBITOR AND RELATED METHODS OF USE | CMG PHARMACEUTICAL CO., LTD. (KR) | 2019-09-26 | — | — | WO | disclosed |