Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21396339 | 0.88 | KDM4E (0.66) | KDM4EMAPTALDH1A1TP53LMNA | |
| SCHEMBL21396337 | 0.87 | MAPT (0.62) | KDM4EMAPTALDH1A1TP53LMNA | |
| SCHEMBL21396336 | 0.84 | KDM4E (0.76) | KDM4EMAPTALDH1A1TP53LMNA | |
| SCHEMBL21396317 | 0.82 | MAPT (0.60) | KDM4EMAPTALDH1A1TP53LMNA | |
| SCHEMBL21378557 | 0.79 | NPC1 (0.52) | KDM4EMAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL21378555 | 0.79 | NPC1 (0.52) | KDM4EMAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL29064129 | 0.77 | PPARG (0.57) | NPC1RAB9ANAPEPLDCFTR | |
| SCHEMBL21396303 | 0.77 | KDM4E (0.72) | KDM4EMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL21396320 | 0.72 | KDM4E (0.49) | KDM4EMAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL31095756 | 0.72 | KDM4E (0.55) | KDM4EMAPTALDH1A1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180686-A1 | IDO-TDO DUAL INHIBITOR AND RELATED METHODS OF USE | CMG PHARMACEUTICAL CO., LTD. (KR) | 2019-09-26 | — | — | WO | disclosed |