Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21396418 | 0.85 | MAPT (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25928360 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL21396392 | 0.70 | TDP1 (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25930115 | 0.69 | MAPT (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23920985 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL25929055 | 0.68 | MAPT (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25929899 | 0.66 | MAPT (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25931274 | 0.66 | MAPT (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25929765 | 0.64 | MAPT (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25929720 | 0.64 | MAPT (0.41) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292214-A1 | NEW EQUATORIALLY MODIFIED POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | MIRECA MEDICINES GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292214-A1 | NEW EQUATORIALLY MODIFIED POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | PDE7A, PRKG1, PDE4C | PDE4A 5/4885PDE4B 13/4885PDE4C 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.