Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 8/20 | 0.43 |
| ▸ | CDK7 | P50613 | 8/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665655 | 1.00 | CCNT1 (0.49) | CCNT1KDM1AMAOAMAOBCDK9 | |
| SCHEMBL18069763 | 0.93 | PIM1 (0.49) | CCNT1CDK9CDK7CSNK1A1CCNH | |
| Hydrochloric Acid SCHEMBL18047351 | 0.92 | PIM1 (0.48) | CCNT1CDK9CDK7CSNK1A1CCNH | |
| SCHEMBL16665183 | 0.83 | CDK7 (0.46) | CCNT1CDK9CDK7CCNHBRAF | |
| SCHEMBL16653686 | 0.79 | CDK7 (0.47) | CCNT1CDK9CDK7CSNK1A1CCNH | |
| SCHEMBL16653683 | 0.79 | CDK7 (0.47) | CCNT1CDK9CDK7CSNK1A1CCNH | |
| SCHEMBL28349716 | 0.78 | CDK7 (0.43) | CCNT1CDK9CDK7CCNHBRAF | |
| SCHEMBL28349718 | 0.78 | CDK7 (0.43) | CCNT1CDK9CDK7CCNHBRAF | |
| SCHEMBL31334650 | 0.78 | ADORA1 (0.52) | CCNT1CDK9CDK7CSNK1A1CCNH | |
| SCHEMBL31333867 | 0.78 | ADORA1 (0.52) | CCNT1CDK9CDK7CSNK1A1CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292167-A1 | HETEROAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | SYROS PHARMACEUTICALS INC (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292167-A1 | HETEROAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | CDK7, CDK3, CDK17 | CCNT1 28/4885KDM1A 1697/4885MAOA 2849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.