Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | USP14 | P54578 | 1/20 | 0.44 |
| ▸ | ATF4 | P18848 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655935 | 0.90 | SUV39H2 (0.54) | SUV39H2DRD2CNR1CNR2DRD3 | |
| SCHEMBL7521871 | 0.85 | SUV39H2 (0.51) | SUV39H2DRD2CNR1CNR2DRD3 | |
| SCHEMBL13466335 | 0.84 | PIM1 (0.45) | SUV39H2CNR1CNR2CKS1BSKP1 | |
| SCHEMBL5220499 | 0.84 | KDM4D (0.53) | SUV39H2DRD2CKS1BSKP1SKP2 | |
| SCHEMBL3108407 | 0.83 | CNR1 (0.55) | SUV39H2DRD2CNR1CNR2DRD3 | |
| SCHEMBL5216885 | 0.83 | CHRM4 (0.53) | SUV39H2DRD2CKS1BSKP1SKP2 | |
| SCHEMBL1350092 | 0.83 | SUV39H2 (0.49) | SUV39H2CKS1BSKP1SKP2KDM4D | |
| SCHEMBL1350090 | 0.83 | SUV39H2 (0.49) | SUV39H2CKS1BSKP1SKP2KDM4D | |
| SCHEMBL14301964 | 0.82 | CKS1B (0.46) | SUV39H2DRD2CKS1BSKP1SKP2 | |
| SCHEMBL25453973 | 0.82 | SUV39H2 (0.50) | SUV39H2DRD2CNR1CNR2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |