Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 2/20 | 0.45 |
| ▸ | FPR2 | P25090 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397172 | 0.83 | MAPT (0.55) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL21397268 | 0.83 | FPR1 (0.45) | FPR1FPR2 | |
| SCHEMBL21187199 | 0.81 | FPR1 (0.47) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL13584154 | 0.74 | MEN1 (0.55) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL21187141 | 0.73 | FPR1 (0.52) | MAPTKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL13234932 | 0.73 | MAPT (1.00) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL13234947 | 0.73 | MAPT (1.00) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL17557716 | 0.73 | MAPT (0.62) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL28432321 | 0.73 | MAPT (0.64) | MAPTKMT2AMEN1LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL13584870 | 0.72 | MEN1 (0.54) | MAPTKMT2AMEN1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |