SCHEMBL21398968

SCHEMBL21398968

Clc1cccc2sc3cc(N(c4ccccc4)c4ccccc4)ccc3c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.38
MCL1 Q07820 2/20 0.38
ALDH1A1 P00352 5/20 0.33
MAPT P10636 4/20 0.33
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
APP P05067 1/20 0.32
OGG1 O15527 1/20 0.32
HDAC3 O15379 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19656415 0.95 MAPK1 (0.35) MAPK1MCL1ALDH1A1MAPTKDM4E
SCHEMBL19656527 0.92 MCL1 (0.33) MAPK1MCL1MAPTSMN1; SMN2
SCHEMBL21398895 0.90 ALDH1A1 (0.37) MAPK1MCL1ALDH1A1MAPTKDM4E
SCHEMBL22925203 0.88 MAPK1 (0.33) MAPK1MCL1ALDH1A1MAPTSMN1; SMN2
SCHEMBL21398782 0.88 MCL1 (0.38) MAPK1MCL1ALDH1A1MAPTKDM4E
SCHEMBL21398963 0.88 AHR (0.40) MAPK1MCL1ALDH1A1MAPTKDM4E
SCHEMBL21398892 0.86 ALDH1A1 (0.32) MAPK1MCL1ALDH1A1MAPTSMN1; SMN2
SCHEMBL21398967 0.86 ALDH1A1 (0.35) MAPK1MCL1ALDH1A1MAPTKDM4E
SCHEMBL21936426 0.86 MAPT (0.41) MCL1ALDH1A1MAPTKDM4EL3MBTL1
SCHEMBL21398951 0.85 ALDH1A1 (0.35) MAPK1MCL1ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210028370-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2021-01-28 US disclosed
US-20190296244-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR DUK SAN NEOLUX CO., LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028370-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREFOR OR51E2, WEE1, SLC39A11 MAPK1 2168/4885MCL1 2060/4885ALDH1A1 1905/4885
US-20190296244-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR OR51E2, WEE2, WEE1 MAPK1 2567/4885MCL1 3320/4885ALDH1A1 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.