Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 2/20 | 0.51 |
| ▸ | FNTB | P49356 | 2/20 | 0.51 |
| ▸ | OSBP | P22059 | 2/20 | 0.49 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.48 |
| ▸ | CDC25A | P30304 | 3/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919551 | 0.85 | FNTA (0.58) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL27545306 | 0.81 | CYP2D6 (0.65) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL23452814 | 0.78 | CYP2D6 (0.53) | NPC1L1USP2LMNAMEN1TP53 | |
| SCHEMBL23452817 | 0.77 | FNTA (0.72) | NPC1L1USP2LMNACYP2D6CYP2C19 | |
| SCHEMBL1312201 | 0.76 | FNTA (0.58) | NPC1L1USP2LMNACYP2D6CYP2C19 | |
| SCHEMBL9018747 | 0.76 | CDC25A (0.61) | NPC1L1USP2LMNAMEN1TP53 | |
| Epicoprosterol SCHEMBL24632942 | 0.75 | OSBP (0.78) | USP2LMNATP53CYP2D6CYP2C19 | |
| Epicoprosterol SCHEMBL21000320 | 0.75 | OSBP (0.78) | USP2LMNATP53CYP2D6CYP2C19 | |
| Epicoprosterol SCHEMBL25267973 | 0.75 | OSBP (0.78) | USP2LMNATP53CYP2D6CYP2C19 | |
| Epicoprosterol SCHEMBL22018677 | 0.75 | OSBP (0.78) | USP2LMNATP53CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182109-A1 | BBB-PASSING LIPID LIGAND OF HETERO NUCLEIC ACID | 国立大学法人東京医科歯科大学 | 2019-09-26 | — | — | WO | disclosed |