Epicoprosterol

Epicoprosterol

SCHEMBL25267973

CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CCC4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OSBP P22059 1/20 0.78
OSBP2 Q969R2 1/20 0.78
CYP2C19 P33261 2/20 0.76
CYP2D6 P10635 1/20 0.76
ST6GAL1 P15907 2/20 0.75
INPP5D Q92835 1/20 0.74
GPBAR1 Q8TDU6 5/20 0.72
CASP7 P55210 3/20 0.72
HIF1A Q16665 3/20 0.72
TP53 P04637 2/20 0.72
MAPK1 P28482 2/20 0.72
HSD17B10 Q99714 2/20 0.72
BLM P54132 2/20 0.72
TDP1 Q9NUW8 2/20 0.72
VDR P11473 2/20 0.72
USP2 O75604 2/20 0.72
LMNA P02545 2/20 0.72
CYP3A4 P08684 2/20 0.72
MDM4 O15151 1/20 0.72
MAPT P10636 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Epicoprosterol SCHEMBL12607072 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL16867279 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL12453190 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL12806627 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL24632942 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL11380074 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL11391325 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL21000320 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epicoprosterol SCHEMBL22018677 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1
Epidihydrocholesterin SCHEMBL776234 1.00 OSBP (0.78) OSBPOSBP2CYP2C19CYP2D6ST6GAL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 US disclosed
US-20250049727-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM ARES CAPITAL CORPORATION, AS AGENT 2025-02-13 US disclosed
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
US-20230285310-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM ARES CAPITAL CORPORATION, AS AGENT 2023-09-14 US disclosed
EP-4192433-A2 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM Modernatx, Inc. (US) 2023-06-14 EP disclosed
WO-2023086465-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM MODERNATX, INC. (US) 2023-05-19 WO disclosed
CN-103314973-B Method for extracting anti-artemia active ingredients from styela canopus GUANGXI ZHUANG AUTONOMOUS REGION INST OCEANOLOGY 2014-06-18 CN disclosed
CN-103314973-A Method for extracting anti-artemia active ingredients from styela canopus GUANGXI ZHUANG AUTONOMOUS REGION INST OCEANOLOGY 2013-09-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049727-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM CFTR, TSLP, MTREX OSBP 855/4885OSBP2 1047/4885CYP2C19 4875/4885
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR OSBP 140/4885OSBP2 82/4885CYP2C19 2443/4885
US-20230285310-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM CFTR, TSLP, MTREX OSBP 855/4885OSBP2 1047/4885CYP2C19 4875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.