Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CES2 | O00748 | 4/20 | 0.67 |
| ▸ | CES1 | P23141 | 4/20 | 0.67 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL31171895 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Decanoic Acid SCHEMBL8385435 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Stearic Acid SCHEMBL18258677 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Dodecanoate SCHEMBL2140158 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Stearic Acid SCHEMBL428882 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Dodecanoate SCHEMBL914943 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Undecanoate SCHEMBL17536058 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Octanoic Acid SCHEMBL848569 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Nonanoate SCHEMBL5590408 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 | |
| Heptanoate SCHEMBL17091706 | 1.00 | FABP3 (0.72) | FABP3CA1CES2CES1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677438-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-110540679-B | Rubber composition for tire and pneumatic tire | 住友橡胶工业株式会社 | 2023-03-31 | — | — | CN | disclosed |
| US-11613144-B2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2023-03-28 | — | — | US | disclosed |
| CN-110540687-B | Rubber composition for tire and pneumatic tire | 住友橡胶工业株式会社 | 2023-03-10 | — | — | CN | disclosed |
| US-11433705-B2 | Studless tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2022-09-06 | — | — | US | disclosed |
| EP-4039503-A1 | RUBBER COMPOSITION AND RUN-FLAT TIRE | BRIDGESTONE CORPORATION (JP) | 2022-08-10 | — | — | EP | disclosed |
| EP-4039502-A1 | RUN-FLAT TIRE | BRIDGESTONE CORPORATION (JP) | 2022-08-10 | — | — | EP | disclosed |
| CN-110382609-B | Studless tire | 住友橡胶工业株式会社 | 2022-03-22 | — | — | CN | disclosed |
| US-20210163719-A1 | SIDE REINFORCEMENT RUBBER COMPOSITION FOR RUN-FLAT TIRE, SIDE REINFORCEMENT RUBBER FOR RUN-FLAT TIRE, AND RUN-FLAT TIRE | BRIDGESTONE CORPORATION (JP) | 2021-06-03 | — | — | US | disclosed |
| US-20200391550-A1 | TREAD RUBBER COMPOSITION FOR STUDLESS WINTER TIRES | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2020-12-17 | — | — | US | disclosed |
| US-20140228525-A1 | RUBBER COMPOSITION AND TIRE USING THE SAME AS WELL AS MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PRODUCING THE SAME | BRIDGESTONE CORPORATION (JP) | 2014-08-14 | — | — | US | disclosed |
| EP-2377693-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2014-06-25 | — | — | EP | disclosed |
| US-8729184-B2 | Rubber composition and tire using the same as well as modified conjugated diene-based polymer and method for producing the same | BRIDGESTONE CORPORATION (JP) | 2014-05-20 | — | — | US | disclosed |
| EP-2471673-A1 | RUN FLAT TIRE | Bridgestone Corporation (JP) | 2012-07-04 | — | — | EP | disclosed |
| US-20120152425-A1 | RUN FLAT TIRE | BRIDGSTONE CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20110290396-A1 | PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2011-12-01 | — | — | US | disclosed |
| EP-2377693-A1 | PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2011-10-19 | — | — | EP | disclosed |
| US-20110184114-A1 | RUBBER COMPOSITION AND TIRE USING THE SAME AS WELL AS MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PRODUCING THE SAME | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | US | disclosed |
| US-20110046263-A1 | TIRE PREPARED BY USING RUBBER COMPOSITION CONTAINING MODIFIED POLYMER | BRIDGESTONE CORPORATION (JP) | 2011-02-24 | — | — | US | disclosed |
| EP-2253664-A1 | RUBBER COMPOSITION AND TIRES USING THE SAME, AS WELL AS MODIFIED CONJUGATE DIENE POLYMER AND MANUFACTURING METHOD THEREOF | Bridgestone Corporation (JP) | 2010-11-24 | — | — | EP | disclosed |