Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SI | P14410 | 3/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21399737 | 0.94 | NR3C1 (0.52) | NR3C1PGRNR3C2ARAHR | |
| SCHEMBL21399618 | 0.93 | NR3C1 (0.62) | NR3C1PGRNR3C2ARAHR | |
| SCHEMBL3342744 | 0.85 | GUSB (0.61) | NR3C1PGRNR3C2ARAHR | |
| SCHEMBL29871366 | 0.85 | GUSB (0.61) | NR3C1PGRNR3C2ARAHR | |
| SCHEMBL21399712 | 0.85 | GUSB (0.53) | NR3C1PGRNR3C2ARAHR | |
| SCHEMBL21383534 | 0.84 | GUSB (0.48) | NR3C1PGRNR3C2ARAHR | |
| SCHEMBL21399352 | 0.83 | GUSB (0.53) | NR3C1PGRNR3C2ARAHR | |
| SCHEMBL29802857 | 0.83 | NR3C1 (0.89) | NR3C1PGRNR3C2ARAHR | |
| SCHEMBL2546810 | 0.83 | NR3C1 (0.89) | NR3C1PGRNR3C2ARAHR | |
| SCHEMBL21399351 | 0.82 | GUSB (0.58) | NR3C1PGRNR3C2ARAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024499-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | XIAMEN UNIVERSITY (CN) | 2021-01-28 | — | — | US | disclosed |
| WO-2019183527-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024499-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | BCL2, BCOR, BCLAF1 | NR3C1 71/4885PGR 893/4885NR3C2 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.