Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21400643 | 0.83 | CCR3 (0.50) | CCR3IDO1CHRM2MGLL | |
| SCHEMBL21381377 | 0.75 | CHRM2 (0.57) | CCR3IDO1CHRM2 | |
| SCHEMBL18840752 | 0.71 | CCR3 (1.00) | CCR3CHRM2 | |
| SCHEMBL21400645 | 0.71 | CCR3 (0.49) | CCR3IDO1CHRM2 | |
| SCHEMBL17729173 | 0.71 | FAAH (0.56) | CCR3IDO1TACR2TACR1 | |
| SCHEMBL17729176 | 0.71 | IDO1 (0.65) | IDO1TACR1 | |
| SCHEMBL17737351 | 0.71 | IDO1 (0.70) | IDO1EPHX2USP30 | |
| SCHEMBL17737260 | 0.71 | IDO1 (0.70) | IDO1EPHX2USP30 | |
| SCHEMBL20852767 | 0.71 | IDO1 (0.70) | IDO1EPHX2USP30 | |
| SCHEMBL13889230 | 0.70 | CCR3 (0.90) | CCR3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630043-B | Compound containing ring, preparation method and application thereof in medicine | 四川科伦博泰生物医药股份有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-111630043-A | Compound containing ring, preparation method and application thereof in medicine | 四川科伦博泰生物医药股份有限公司 | 2020-09-04 | — | — | CN | disclosed |
| WO-2019179369-A1 | RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |