Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 10/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401173 | 0.84 | ADRA2A (0.74) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL21401161 | 0.84 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL21401165 | 0.81 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL3064400 | 0.79 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL27905456 | 0.79 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL3051753 | 0.77 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL2626831 | 0.74 | ADRA2A (0.63) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL2626809 | 0.74 | ADRA2A (0.63) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL2626832 | 0.74 | ADRA2A (0.63) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL2626795 | 0.73 | ADRA2A (0.63) | ADRA2AADRA2BADRA2CADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206727-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | UNIV OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2021-07-08 | — | — | US | disclosed |
| US-10766866-B2 | Deterrents for arthropods and marine organisms | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH (US) | 2020-09-08 | — | — | US | disclosed |
| US-20190292156-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER AT FORT WORTH | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766866-B2 | Deterrents for arthropods and marine organisms | ALG1, NISCH, ALG8 | ADRA2A 1749/4885ADRA2B 3315/4885ADRA2C 1733/4885 |
| US-20210206727-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | ALG1, ALG8, DDT | ADRA2A 1871/4885ADRA2B 3416/4885ADRA2C 1878/4885 |
| US-20190292156-A1 | DETERRENTS FOR ARTHROPODS AND MARINE ORGANISMS | ALG1, NISCH, ALG8 | ADRA2A 1749/4885ADRA2B 3315/4885ADRA2C 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.