SCHEMBL21402297

SCHEMBL21402297

COc1ccc(CCOCCc2ccc(OC)c(O)c2)cc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.69
CYP1A2 P05177 1/20 0.69
CYP3A4 P08684 1/20 0.69
NFKB1 P19838 1/20 0.69
LMNA P02545 2/20 0.67
MEN1 O00255 1/20 0.67
APEX1 P27695 1/20 0.67
KMT2A Q03164 1/20 0.67
TUBB4A P04350 5/20 0.65
TUBB P07437 5/20 0.65
TUBA3C P0DPH7 5/20 0.65
TUBA1B P68363 5/20 0.65
TUBA4A P68366 5/20 0.65
TUBB4B P68371 5/20 0.65
TUBB3 Q13509 5/20 0.65
TUBB2A Q13885 5/20 0.65
TUBB8 Q3ZCM7 5/20 0.65
TUBA3E Q6PEY2 5/20 0.65
TUBA1A Q71U36 5/20 0.65
TUBA1C Q9BQE3 5/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10763724 0.85 TAAR1 (0.71) TSHRCYP3A4NFKB1LMNAGAA
SCHEMBL2632685 0.83 TSHR (0.71) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL29833121 0.83 CYP3A4 (0.71) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL901444 0.83 CYP3A4 (0.71) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL3815066 0.82 ATM (0.66) CYP1A2CYP3A4KMT2ACYP19A1
SCHEMBL23272810 0.82 TUBB4A (0.67) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL30873175 0.81 TUBB4A (0.70) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL5181048 0.81 TSHR (0.69) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL8938305 0.81 TSHR (0.69) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL30873093 0.81 TUBB4A (0.75) TSHRCYP1A2CYP3A4NFKB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108366597-B Substance mixture 西姆莱斯有限公司 2022-09-02 CN claimed
EP-3569671-B1 METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME TAKASAGO PERFUMERY CO LTD (JP) 2022-06-22 EP claimed
EP-3275962-B1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TAKASAGO PERFUMERY CO LTD (JP) 2019-10-02 EP claimed