Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 4/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2727243 | 0.81 | DYRK1A (0.36) | HTTSMN1; SMN2NPSR1ALDH1A1MAPT | |
| SCHEMBL14895067 | 0.79 | DYRK1A (0.39) | HTTSMN1; SMN2NPSR1ALDH1A1MAPT | |
| SCHEMBL28963467 | 0.75 | PARP1 (0.38) | — | |
| SCHEMBL21403557 | 0.75 | DYRK1A (0.32) | NQO2DYRK1A | |
| SCHEMBL31354048 | 0.75 | HTT (0.33) | HTTDYRK1AKMT2APTGES | |
| SCHEMBL21403775 | 0.74 | HTT (0.41) | HTTSMN1; SMN2NPSR1ALDH1A1MAPT | |
| SCHEMBL30059116 | 0.74 | HTT (0.41) | HTTSMN1; SMN2NPSR1ALDH1A1MAPT | |
| SCHEMBL14895071 | 0.73 | DYRK1A (0.42) | ALDH1A1DYRK1AKDM4E | |
| SCHEMBL7427955 | 0.73 | MPO (0.46) | HTTALDH1A1NQO2KMT2A | |
| SCHEMBL4978434 | 0.72 | DYRK1A (0.37) | HTTSMN1; SMN2NPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4566675-A2 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | Incyte Corporation (US) | 2025-06-11 | — | — | EP | disclosed |
| US-20250171443-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2025-05-29 | — | — | US | disclosed |
| CN-119613400-A | Heterocyclic compounds as immunomodulators | 因赛特公司 | 2025-03-14 | — | — | CN | disclosed |
| US-12247026-B2 | Heterocyclic compounds as immunomodulators | INCYTE CORPORATION (US) | 2025-03-11 | — | — | US | disclosed |
| EP-4212529-B1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORP (US) | 2025-01-29 | — | — | EP | disclosed |
| CN-112135824-B | Heterocyclic compounds as immunomodulators | 因赛特公司 | 2024-11-05 | — | — | CN | disclosed |
| EP-4212529-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | Incyte Corporation (US) | 2023-07-19 | — | — | EP | disclosed |
| EP-3774791-B1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORP (US) | 2022-12-21 | — | — | EP | disclosed |
| US-20210380584-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2021-12-09 | — | — | US | disclosed |
| US-11124511-B2 | Heterocyclic compounds as immunomodulators | INCYTE CORPORATION (US) | 2021-09-21 | — | — | US | disclosed |
| EP-3774791-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | Incyte Corporation (US) | 2021-02-17 | — | — | EP | disclosed |
| CN-112135824-A | Heterocyclic compounds as immunomodulators | 因赛特公司 | 2020-12-25 | — | — | CN | disclosed |
| US-20200255424-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2020-08-13 | — | — | US | disclosed |
| US-10669271-B2 | Heterocyclic compounds as immunomodulators | INCYTE CORPORATION (US) | 2020-06-02 | — | — | US | disclosed |
| WO-2019191707-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION (US) | 2019-10-03 | — | — | WO | disclosed |
| US-20190300524-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300524-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD74, IL2, ICOS | HTT 3758/4885SMN1; SMN2 4119/4885NPSR1 1786/4885 |
| US-10669271-B2 | Heterocyclic compounds as immunomodulators | CD74, IL2, ICOS | HTT 3758/4885SMN1; SMN2 4119/4885NPSR1 1786/4885 |
| US-20200255424-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD74, IL2, ICOS | HTT 3758/4885SMN1; SMN2 4119/4885NPSR1 1786/4885 |
| US-20210380584-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD74, IL2, ICOS | HTT 3758/4885SMN1; SMN2 4119/4885NPSR1 1786/4885 |
| US-11124511-B2 | Heterocyclic compounds as immunomodulators | CD74, IL2, ICOS | HTT 3758/4885SMN1; SMN2 4119/4885NPSR1 1786/4885 |
| US-12247026-B2 | Heterocyclic compounds as immunomodulators | CD74, IL2, ICOS | HTT 3758/4885SMN1; SMN2 4119/4885NPSR1 1786/4885 |
| US-20250171443-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD74, IL2, ICOS | HTT 3758/4885SMN1; SMN2 4119/4885NPSR1 1786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.