Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214068 | 1.00 | PLA2G7 (0.49) | PLA2G7LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL214069 | 1.00 | PLA2G7 (0.49) | PLA2G7LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5819792 | 0.89 | MAPT (0.50) | PLA2G7LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17256876 | 0.85 | NPC1 (0.62) | PLA2G7LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17256878 | 0.85 | NPC1 (0.62) | PLA2G7LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17256880 | 0.85 | NPC1 (0.62) | PLA2G7LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2045290 | 0.82 | TSHR (0.50) | LMNARAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL11522499 | 0.82 | TSHR (0.50) | LMNARAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL31220250 | 0.80 | GRIN1 (0.46) | PLA2G7LMNARAB9AMAOBGRIN1 | |
| SCHEMBL31220357 | 0.78 | KMT2A (0.46) | LMNARAB9ANPC1SMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| US-8541509-B2 | Polymers functionalized with protected oxime compounds | BRIDGESTONE CORPORATION (JP) | 2013-09-24 | — | — | US | disclosed |
| EP-1913036-B1 | AMINE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORP (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | disclosed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-7820765-B2 | Amine functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20100120976-A1 | AMINE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2010-05-13 | — | — | US | disclosed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | disclosed |