Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397922 | 0.97 | — | — | |
| SCHEMBL3401418 | 0.97 | — | — | |
| SCHEMBL41064 | 0.97 | — | — | |
| SCHEMBL19411359 | 0.94 | LMNA (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL830579 | 0.94 | LMNA (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL10406986 | 0.94 | LMNA (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| 1,6-Hexanediol SCHEMBL15347446 | 0.94 | LMNA (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL428372 | 0.94 | LMNA (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL13202549 | 0.94 | LMNA (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL554360 | 0.94 | LMNA (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11116211-B2 | Modification of segmented polyurethane properties by copolymerizing with pendant functionalized diols | THE UNIVERSITY OF AKRON (US) | 2021-09-14 | — | — | US | disclosed |
| US-20190297883-A1 | Modification of Segmented Polyurethane Properties by Copolymerizing with Pendant Functionalized Diols | THE UNIVERSITY OF AKRON | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190297883-A1 | Modification of Segmented Polyurethane Properties by Copolymerizing with Pendant Functionalized Diols | SMCHD1, PUF60, DNER | TDP1 1639/4885SMN1; SMN2 1189/4885TSHR 2204/4885 |
| US-11116211-B2 | Modification of segmented polyurethane properties by copolymerizing with pendant functionalized diols | SMCHD1, PUF60, DNER | TDP1 1639/4885SMN1; SMN2 1189/4885TSHR 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.