SCHEMBL21409558

SCHEMBL21409558

[CH]=CC/C=C/C/C=C/CCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.57
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 3/20 0.55
F7 P08709 3/20 0.55
F3 P13726 3/20 0.55
PPARG P37231 3/20 0.55
PPARD Q03181 2/20 0.55
PPARA Q07869 2/20 0.55
FABP3 P05413 2/20 0.55
DUSP3 P51452 1/20 0.55
PTPN7 P35236 1/20 0.55
FFAR1 O14842 1/20 0.55
LMNA P02545 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP19A1 P11511 1/20 0.55
FABP4 P15090 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55
PTGS1 P23219 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29284430 1.00 TRPV1 (0.57) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL21409559 1.00 TRPV1 (0.57) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL28637577 1.00 TRPV1 (0.57) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL7289670 0.98 FAAH (0.54) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL25181797 0.98 FAAH (0.54) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL25182431 0.98 FAAH (0.54) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL7289665 0.98 FAAH (0.54) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL21694666 0.98 FAAH (0.54) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL25178025 0.98 FAAH (0.54) TRPV1ALDH1A1KDM4EF7F3
SCHEMBL21694668 0.98 FAAH (0.54) TRPV1ALDH1A1KDM4EF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11901249-B2 Curable composition and cured product thereof DIC CORPORATION (JP) 2024-02-13 US disclosed
US-11873356-B2 Curable composition and cured product thereof DIC CORPORATION (JP) 2024-01-16 US disclosed
US-11548977-B2 Active ester resin and composition and cured product using the same DIC CORPORATION (JP) 2023-01-10 US disclosed
US-11407708-B2 Active ester compound and composition and cured product obtained using the same DIC CORPORATION (JP) 2022-08-09 US disclosed
US-20210032383-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF DIC CORPORATION (JP) 2021-02-04 US disclosed
US-20210009804-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF DIC CORPORATION (JP) 2021-01-14 US disclosed
CN-112119104-A Epoxy (meth) acrylate resin composition, curable resin composition, cured product, and article DIC株式会社 2020-12-22 CN disclosed
CN-112105661-A Acid group-containing (meth) acrylate resin composition, curable resin composition, cured product, insulating material, resin material for solder resist, and protective member DIC株式会社 2020-12-18 CN disclosed
CN-111971323-A Curable composition and cured product thereof DIC株式会社 2020-11-20 CN disclosed
US-20200216603-A1 ACTIVE ESTER RESIN AND COMPOSITION AND CURED PRODUCT USING THE SAME DIC CORPORATION (JP) 2020-07-09 US disclosed
US-20200207700-A1 ACTIVE ESTER COMPOUND AND COMPOSITION AND CURED PRODUCT OBTAINED USING THE SAME DIC CORPORATION (JP) 2020-07-02 US disclosed
WO-2019188332-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF DIC株式会社 2019-10-03 WO disclosed
WO-2019188330-A1 CURABLE COMPOSITION AND CURED PRODUCT OF SAME DIC株式会社 2019-10-03 WO disclosed
WO-2019188333-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF DIC株式会社 2019-10-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200207700-A1 ACTIVE ESTER COMPOUND AND COMPOSITION AND CURED PRODUCT OBTAINED USING THE SAME CRAT, CYP19A1, EP300 TRPV1 248/4885ALDH1A1 19/4885KDM4E 479/4885
US-11407708-B2 Active ester compound and composition and cured product obtained using the same CRAT, CYP19A1, EP300 TRPV1 248/4885ALDH1A1 19/4885KDM4E 479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.