SCHEMBL214110

SCHEMBL214110

CC(C)COC(=O)N1c2ccccc2C=CC1OCC(C)C

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.69
LMNA P02545 2/20 0.69
P2RX4 Q99571 7/20 0.60
ALDH1A1 P00352 5/20 0.42
TSHR P16473 2/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
P2RX1 P51575 3/20 0.40
P2RX3 P56373 3/20 0.40
P2RX7 Q99572 2/20 0.40
NPSR1 Q6W5P4 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPK1 P28482 1/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
PTBP1 P26599 1/20 0.35
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20840679 1.00 SMN1; SMN2 (0.69) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR
SCHEMBL29427926 1.00 SMN1; SMN2 (0.69) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR
SCHEMBL17633849 1.00 SMN1; SMN2 (0.69) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR
SCHEMBL7284649 0.94 SMN1; SMN2 (0.79) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR
SCHEMBL5862557 0.93 SMN1; SMN2 (0.81) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR
SCHEMBL5862606 0.90 SMN1; SMN2 (0.62) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR
SCHEMBL13268519 0.89 LMNA (0.64) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR
SCHEMBL4612051 0.88 SMN1; SMN2 (0.56) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR
Quinoline SCHEMBL15147615 0.88 SMN1; SMN2 (0.54) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR
SCHEMBL20358130 0.87 SMN1; SMN2 (0.57) SMN1; SMN2LMNAP2RX4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 973 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504708-A Method for preparing lebol Lei Sheng without adding organic amine 上海奥博生物医药股份有限公司 2025-02-25 CN claimed
CN-118772124-A Preparation method of Suzetrigine 山东福长药业有限公司 2024-10-15 CN claimed
CN-118620022-A Process for preparing phosphorylated polypeptides 南京金斯瑞生物科技有限公司 2024-09-10 CN claimed
EP-4384501-A1 PROCESS FOR THE PREPARATION OF OLAPARIB, AND CRYSTALLINE FORM THEREOF Glenmark Life Sciences Limited (IN) 2024-06-19 EP claimed
CN-117903065-A Synthesis method of 2-sulfonyl pyrimidine-4-carboxamide compound II 西北师范大学 2024-04-19 CN claimed
CN-117903064-A 2-Sulfonyl pyrimidine-4-carboxamide compound I and synthetic method thereof 西北师范大学 2024-04-19 CN claimed
CN-117626671-B Blended fabric based on natural deodorizing modified regenerated fibers 比音勒芬服饰股份有限公司 2024-03-22 CN claimed
CN-117626671-A Blended fabric based on natural deodorizing modified regenerated fibers 比音勒芬服饰股份有限公司 2024-03-01 CN claimed
CN-117466763-A Preparation method of 2, 2-bis [3- (3-aminobenzoylamino) -4-hydroxyphenyl ] hexafluoropropane 天津众泰材料科技有限公司 2024-01-30 CN claimed
WO-2023017393-A1 PROCESS FOR THE PREPARATION OF OLAPARIB, AND CRYSTALLINE FORM THEREOF GLENMARK LIFE SCIENCES LIMITED (IN) 2023-02-16 WO claimed
US-20080318336-A1 Labels, Their Production Process And Their Uses LABORATOIRES SYNTH-INNOVE (FR) 2008-12-25 US claimed
WO-2008092955-A1 PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV TIBOTEC PHARMACEUTICALS LTD. (IE) 2008-08-07 WO claimed
CN-1434795-A Acylated Pseudodipeptides with Functionalized Auxiliary Branches OM PHARMA (CH) 2003-08-06 CN claimed
JP-2003518086-A 2003-06-03 JP claimed
EP-1242365-A1 ACYL PSEUDODIPEPTIDES WHICH CARRY A FUNCTIONALISED AUXILIARY ARM OM Pharma (CH) 2002-09-25 EP claimed
WO-2001046126-A1 ACYL PSEUDODIPEPTIDES WHICH CARRY A FUNCTIONALISED AUXILIARY ARM OM PHARMA (CH) 2001-06-28 WO claimed
US-5294696-A Process for producing polyisoimide CHISSO CORPORATION (JP) 1994-03-15 US claimed
EP-0567637-A1 BIS(PERFLUOROSULPHONYL)METHANES, PROCESS FOR PREPARING SAME AND USES THEREOF Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1993-11-03 EP claimed
WO-1993009092-A1 BIS(PERFLUOROSULPHONYL)METHANES, PROCESS FOR PREPARING SAME AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1993-05-13 WO claimed
US-4617301-A Sulfoxide and sulfone derivatives of bicyclic lactams as antihypertensives MERCK & CO., INC. (US) 1986-10-14 US claimed