Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.37 |
| ▸ | FABP7 | O15540 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21411551 | 1.00 | CTSL (0.38) | CTSLCTSSCTSKFABP5FABP7 | |
| SCHEMBL6317064 | 1.00 | CTSL (0.38) | CTSLCTSSCTSKFABP5FABP7 | |
| SCHEMBL31369420 | 0.85 | KMT2A (0.48) | FABP5FABP7KMT2ACASP3 | |
| SCHEMBL29981793 | 0.84 | CTNNB1 (0.39) | FABP5FABP7KMT2ACASP3 | |
| SCHEMBL119785 | 0.84 | CTNNB1 (0.39) | FABP5FABP7KMT2ACASP3 | |
| SCHEMBL16108213 | 0.84 | CTNNB1 (0.39) | FABP5FABP7KMT2ACASP3 | |
| SCHEMBL119780 | 0.84 | CTNNB1 (0.39) | FABP5FABP7KMT2ACASP3 | |
| SCHEMBL25182166 | 0.83 | FABP5 (0.40) | FABP5FABP7KMT2ACASP3 | |
| SCHEMBL30055228 | 0.83 | FABP5 (0.40) | FABP5FABP7KMT2ACASP3 | |
| SCHEMBL24633714 | 0.83 | FABP5 (0.40) | FABP5FABP7KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774850-A1 | CDP PROTEIN SECRETION INHIBITORS | Kezar Life Sciences (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019191527-A1 | CDP PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019191527-A1 | CDP PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-10-03 | — | — | WO | disclosed |