Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 18/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 8/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21417005 | 0.81 | CHRNA7 (0.55) | CHRNA7HTR3A | |
| SCHEMBL21417038 | 0.80 | CHRNA7 (0.50) | CHRNA7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21417305 | 0.80 | HDAC3 (0.59) | CHRNA7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21417331 | 0.79 | CHRNA7 (0.52) | CHRNA7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20661376 | 0.78 | CHRNA7 (0.50) | CHRNA7HTR3A | |
| SCHEMBL21416981 | 0.77 | CHRNA7 (0.54) | CHRNA7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21417050 | 0.77 | CHRNA7 (0.54) | CHRNA7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21417360 | 0.77 | CHRNA7 (0.56) | CHRNA7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21417096 | 0.75 | CHRNA7 (0.56) | CHRNA7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21417095 | 0.70 | EPHX1 (0.47) | CHRNA7HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233087-B1 | GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTORS | AXOVANT SCIENCES GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |