Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17725393 | 1.00 | LIG1 (0.42) | LIG1KDM1ARCOR1SLC6A2SLC6A4 | |
| SCHEMBL21418971 | 1.00 | LIG1 (0.42) | LIG1KDM1ARCOR1SLC6A2SLC6A4 | |
| SCHEMBL19629557 | 1.00 | LIG1 (0.42) | LIG1KDM1ARCOR1SLC6A2SLC6A4 | |
| SCHEMBL19626353 | 1.00 | LIG1 (0.42) | LIG1KDM1ARCOR1SLC6A2SLC6A4 | |
| SCHEMBL17725137 | 1.00 | LIG1 (0.42) | LIG1KDM1ARCOR1SLC6A2SLC6A4 | |
| SCHEMBL23466168 | 1.00 | LIG1 (0.42) | LIG1KDM1ARCOR1SLC6A2SLC6A4 | |
| SCHEMBL20840859 | 0.83 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3SLC6A9OPRM1 | |
| SCHEMBL21836832 | 0.83 | LIG1 (0.42) | LIG1KDM1ARCOR1SLC6A2SLC6A4 | |
| SCHEMBL19626342 | 0.83 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3SLC6A9OPRM1 | |
| SCHEMBL19629563 | 0.82 | HTR2A (0.44) | KDM1AOPRM1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654842-B2 | Dopamine D3 receptor antagonist compounds | INDIVIOR UK LIMITED (GB) | 2020-05-19 | — | — | US | disclosed |
| US-20190300514-A1 | DOPAMINE D3 RECEPTOR ANTAGONIST COMPOUNDS | INDIVIOR INC. | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654842-B2 | Dopamine D3 receptor antagonist compounds | DRD3, DRD2, DRD4 | LIG1 4048/4885KDM1A 3812/4885RCOR1 2748/4885 |
| US-20190300514-A1 | DOPAMINE D3 RECEPTOR ANTAGONIST COMPOUNDS | DRD3, DRD2, DRD4 | LIG1 4048/4885KDM1A 3812/4885RCOR1 2748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.