Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 20/20 | 0.87 |
| ▸ | SUZ12 | Q15022 | 20/20 | 0.87 |
| ▸ | EZH2 | Q15910 | 20/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21419397 | 0.95 | EED (0.88) | EEDSUZ12EZH2 | |
| SCHEMBL21419293 | 0.93 | EED (1.00) | EEDSUZ12EZH2 | |
| SCHEMBL21419321 | 0.91 | EZH2 (1.00) | EEDSUZ12EZH2 | |
| SCHEMBL21419366 | 0.90 | EED (0.90) | EEDSUZ12EZH2 | |
| SCHEMBL21419305 | 0.89 | EED (0.88) | EEDSUZ12EZH2 | |
| SCHEMBL21419335 | 0.88 | EED (0.90) | EEDSUZ12EZH2 | |
| SCHEMBL21419390 | 0.87 | EED (0.85) | EEDSUZ12EZH2 | |
| SCHEMBL21404042 | 0.86 | EED (1.00) | EEDSUZ12EZH2 | |
| SCHEMBL21419426 | 0.86 | EZH2 (0.89) | EEDSUZ12EZH2 | |
| SCHEMBL21419294 | 0.86 | EED (0.88) | EEDSUZ12EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793549-B2 | Sulfuryl-substituted benzoheterocyclic derivative, preparation method and medical use thereof | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2020-10-06 | — | — | US | disclosed |
| US-20190300506-A1 | SULFONYL-SUBSTITUTED BENZOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD AND MEDICAL USE THEREOF | YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD. (CN) | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300506-A1 | SULFONYL-SUBSTITUTED BENZOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD AND MEDICAL USE THEREOF | STS, SLC5A2, SULT2A1 | EED 3541/4885SUZ12 1046/4885EZH2 3055/4885 |
| US-10793549-B2 | Sulfuryl-substituted benzoheterocyclic derivative, preparation method and medical use thereof | STS, SULT2A1, CYP2A13 | EED 2953/4885SUZ12 519/4885EZH2 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.