Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | TYK2 | P29597 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21430701 | 0.81 | CA1 (0.39) | CA1CA9JAK2JAK1TYK2 | |
| SCHEMBL9765298 | 0.68 | CA1 (0.45) | CA1CA9KMT2AKDM4EMAPT | |
| SCHEMBL795901 | 0.67 | JAK2 (0.42) | JAK2JAK1TYK2JAK3KCNQ3 | |
| SCHEMBL1514753 | 0.67 | NR1I2 (0.54) | JAK2JAK1TYK2JAK3KCNQ3 | |
| SCHEMBL21430465 | 0.67 | NR1I2 (0.54) | JAK2JAK1TYK2JAK3KCNQ3 | |
| SCHEMBL21430201 | 0.67 | NR1I2 (0.54) | JAK2JAK1TYK2JAK3KCNQ3 | |
| SCHEMBL21430706 | 0.67 | NR1I2 (0.54) | JAK2JAK1TYK2JAK3KCNQ3 | |
| SCHEMBL21430174 | 0.67 | NR1I2 (0.54) | JAK2JAK1TYK2JAK3KCNQ3 | |
| SCHEMBL21085331 | 0.66 | MEN1 (0.46) | JAK2JAK1TYK2JAK3KCNQ3 | |
| SCHEMBL20358182 | 0.65 | MEN1 (0.45) | JAK2JAK1TYK2JAK3KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183793-A1 | N-HYDROXYPYRIDONE COMPOUND AND USE THEREOF | 华东理工大学 | 2019-10-03 | — | — | WO | disclosed |