Glutamine

Glutamine

SCHEMBL2143276

NC(=O)CCC(N)C(=O)O.NCCCCC(N)C(=O)O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.77
BLM P54132 2/20 0.73
KMT2A Q03164 2/20 0.73
ALOX15 P16050 1/20 0.73
PMP22 Q01453 1/20 0.73
CYP1A2 P05177 3/20 0.52
GRM8 O00222 1/20 0.52
GRM6 O15303 1/20 0.52
GRIN2D O15399 1/20 0.52
GRIN3B O60391 1/20 0.52
GRIK1 P39086 1/20 0.52
GRM5 P41594 1/20 0.52
GRIA1 P42261 1/20 0.52
GRIA2 P42262 1/20 0.52
GRIA3 P42263 1/20 0.52
SLC1A3 P43003 1/20 0.52
SLC1A2 P43004 1/20 0.52
SLC1A1 P43005 1/20 0.52
GRIA4 P48058 1/20 0.52
GRIN1 Q05586 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL28030897 1.00 GSR (0.77) GSRBLMKMT2AALOX15PMP22
Glutamine SCHEMBL1812362 1.00 GSR (0.77) GSRBLMKMT2AALOX15PMP22
Glutamine SCHEMBL1347541 1.00 GSR (0.77) GSRBLMKMT2AALOX15PMP22
Glutamine SCHEMBL5461649 1.00 GSR (0.77) GSRBLMKMT2AALOX15PMP22
Glutamine SCHEMBL12468749 1.00 GSR (0.77) GSRBLMKMT2AALOX15PMP22
Glutamine SCHEMBL14485689 0.98 GSR (0.74) GSRBLMKMT2AALOX15PMP22
Glutamine SCHEMBL29022149 0.98 GSR (0.74) GSRBLMKMT2AALOX15PMP22
Glutamine SCHEMBL19743900 0.98 GSR (0.74) GSRBLMKMT2AALOX15PMP22
Glutamine SCHEMBL29022151 0.98 GSR (0.74) GSRBLMKMT2AALOX15PMP22
Glutamine SCHEMBL19743899 0.98 GSR (0.74) GSRBLMKMT2AALOX15PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119816287-A Encapsulation composition and cosmetic or pharmaceutical composition comprising liquid crystal particles and method for producing the same ELC管理有限责任公司 2025-04-11 CN claimed
CN-118382424-A Personal care compositions 高露洁-棕榄公司 2024-07-23 CN claimed
CN-118267303-A Cosmetic material composition, preparation method thereof and cosmetic 上海如妍化妆品有限公司 2024-07-02 CN claimed
CN-114939070-B Flexible liposome of water-soluble active substance and preparation method thereof 上海百雀羚生物科技有限公司 2024-06-28 CN claimed
CN-118236281-A Composition for stabilizing poorly soluble component and cosmetic composition containing same 株式会社LG生活健康 2024-06-25 CN claimed
CN-118217169-A Extremely low-viscosity nano emulsion and preparation method thereof 莹特丽科技(苏州工业园区)有限公司 2024-06-21 CN claimed
CN-118178277-A Flexible liposome coated oil-soluble anti-aging composition, and preparation method and application thereof 上海原萃生物科技有限公司 2024-06-14 CN claimed
CN-118001185-A W/O/W multi-structure sun-screening emulsion and preparation method thereof 上海澄穆化妆品有限公司 2024-05-10 CN claimed
CN-117838583-A Anti-photoaging skin care composition and preparation method and application thereof 山东福瑞达生物股份有限公司 2024-04-09 CN claimed
CN-115813832-B Composition and eye cream for improving eye contour, and preparation method and application thereof 麦吉丽生物科技有限公司 2024-04-05 CN claimed
CN-110934782-A Moisturizing and hand-protecting cream containing deep seawater and preparation method thereof 广州市拉凯尔干细胞研究所 2020-03-31 CN claimed
US-8188012-B2 Process of using hard brine at high alkalinity for enhanced oil recovery (EOR) applications BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-05-29 US claimed
EP-1292615-B1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH CORP (US) 2006-10-25 EP claimed
CN-1676015-A Glutamine transferase soy-bean protein fish and meat product and the like SORENSEN JOHIN T (US) 2005-10-05 CN claimed
US-6664066-B2 Mutant measles virus V protein; gene expression and engineering WYETH HOLDINGS CORPORATION 2003-12-16 US claimed
US-20030206925-A1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH HOLDINGS CORPORATION 2003-11-06 US claimed
EP-0832115-A1 PROMOTION OF HOMOLOGOUS DNA PAIRING BY RecA-DERIVED PEPTIDES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-04-01 EP claimed
WO-1996040765-A1 PROMOTION OF HOMOLOGOUS DNA PAIRING BY RecA-DERIVED PEPTIDES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-12-19 WO claimed
WO-1996016982-A2 ULTRASELECTIVE OPIOIDMIMETIC PEPTIDES AND PHARMACOLOGICAL AND THERAPEUTIC USES THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-06-06 WO claimed
EP-0149581-B1 COMPOSITIONS CONTAINING OLIGO-MURAMYLPEPTIDES AND THEIR APPLICATION, IN PARTICULAR FOR THE ACTIVATION OF MACROPHAGES ANVAR Agence Nationale de Valorisation de la Recherche (FR) 1987-07-22 EP claimed