Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL29022151 | 1.00 | GSR (0.74) | GSRBLMKMT2AALOX15PMP22 | |
| Glutamine SCHEMBL5461649 | 0.98 | GSR (0.77) | GSRBLMKMT2AALOX15PMP22 | |
| Glutamine SCHEMBL1812362 | 0.98 | GSR (0.77) | GSRBLMKMT2AALOX15PMP22 | |
| Glutamine SCHEMBL2143276 | 0.98 | GSR (0.77) | GSRBLMKMT2AALOX15PMP22 | |
| Glutamine SCHEMBL12468749 | 0.98 | GSR (0.77) | GSRBLMKMT2AALOX15PMP22 | |
| Glutamine SCHEMBL28030897 | 0.98 | GSR (0.77) | GSRBLMKMT2AALOX15PMP22 | |
| Glutamine SCHEMBL1347541 | 0.98 | GSR (0.77) | GSRBLMKMT2AALOX15PMP22 | |
| Glutamine SCHEMBL14485689 | 0.96 | GSR (0.74) | GSRBLMKMT2AALOX15PMP22 | |
| Glutamine SCHEMBL19743900 | 0.96 | GSR (0.74) | GSRBLMKMT2AALOX15PMP22 | |
| Glutamine SCHEMBL19743899 | 0.96 | GSR (0.74) | GSRBLMKMT2AALOX15PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116327652-B | Skin anti-aging composition and preparation method thereof | 杭州睿研前瞻生物科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-116158990-B | Composition for relieving sunken scars and preparation method thereof | 包头市中心医院 | 2023-06-30 | — | — | CN | claimed |
| CN-116327652-A | Skin anti-aging composition and preparation method thereof | 杭州睿研前瞻生物科技有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116158990-A | Composition for relieving sunken scars and preparation method thereof | 包头市中心医院 | 2023-05-26 | — | — | CN | claimed |
| CN-115887322-B | Whitening and freckle removing, skin smoothing and moisturizing essence and preparation method thereof | 北京植物医生生物科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-117257694-A | Emulsifier composition and preparation method and application thereof | 长沙黛西生物科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116889539-A | Composition for relieving and resisting allergy, and preparation method and application thereof | 天地慈(东莞)生物科技有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-116158990-B | Composition for relieving sunken scars and preparation method thereof | 包头市中心医院 | 2023-06-30 | — | — | CN | disclosed |
| CN-116158990-A | Composition for relieving sunken scars and preparation method thereof | 包头市中心医院 | 2023-05-26 | — | — | CN | disclosed |