SCHEMBL21436775

SCHEMBL21436775

C#CCNCCS(C)(=O)=O

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SAT1 P21673 1/20 0.41
NLRP3 Q96P20 1/20 0.36
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL680277 0.79 NLRP3 (0.39) NLRP3CA2
SCHEMBL28746280 0.76 NLRP3 (0.52) NLRP3CA2
SCHEMBL14230529 0.74 NLRP3 (0.34) NLRP3CA2
SCHEMBL12847807 0.74 SAT1 (0.36) SAT1
SCHEMBL11798220 0.73 SAT1 (0.57) SAT1
SCHEMBL9403642 0.72
SCHEMBL20377689 0.71 SAT1 (0.47) SAT1
SCHEMBL16449386 0.70 NLRP3 (0.33) NLRP3CA2
SCHEMBL6979353 0.70 CA1 (0.42) NLRP3CA2
SCHEMBL1219894 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019195056-A1 METHODS, COMPOSITIONS, AND IMPLANTABLE ELEMENTS COMPRISING STEM CELLS SIGILON THERAPEUTICS, INC. (US) 2019-10-10 WO disclosed
CN-103159741-A Preparation and application of novel tyrosine kinase inhibitor TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE 2013-06-19 CN disclosed
CN-102627632-A Amino quinazoline derivative and preparation method as well as application thereof GUANGZHOU INST BIOMED & HEALTH 2012-08-08 CN disclosed