Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28932740 | 0.89 | KMT2A (0.36) | MAPK1L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL21219198 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL28541140 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL29172775 | 0.84 | KDM4E (0.38) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL3889830 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL22973084 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL21751770 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL28559501 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL28631026 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL28351010 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-3774789-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |
| WO-2019195201-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |